Are Biphosphonates Safe?

by Jennifer Bunn, RN

Fosamax (alendronate sodium) is one drug in a class of drugs known as biphosponates. Biphosphonates are medications prescribed to prevent or treat osteoporosis. More and more, physicians are also prescribing biphosphonates to patients who have osteopenia, the precursor to osteoporosis.

There is new information coming to light that suggests that women taking biphosphonates for longer than five years may be at increased risk for bone fracture. This may seem odd, considering that Fosamax and others in this drug class are supposed to make bones stronger, but there have been several reports of women on long-term therapy experiencing fractures with little provocation.

Merck, the company that makes Fosamax, has included a warning on the drug information material stating that bone fractures are a possible effect of the drug, but there are no prescribing instructions as to how long women should take Fosamax. As a result of these reports of bone fractures, many physicians are recommending that their patients only stay on the drug for a maximum of five years.

Osteoporosis is a condition in which bones become weak and are more susceptible to fracture. Fractures commonly occur in the wrist, spine, and hip. Older women are at the highest risk for osteoporosis. Smoking, menopause, a sedentary lifestyle and small size (being thin) can also contribute to the development of the condition. Prevention is aimed at ensuring a diet that is rich in calcium and vitamin D and weight-bearing exercise. Avoiding smoking and excessive use of alcohol can also help in prevention of the disease.

PreMenora+ is a formulation of all-natural botanicals to help reduce the symptoms of perimenopause. In addition, PreMenora+ also contains oyster shell calcium and vitamin D, both of which can help to prevent osteoporosis.

Source: Osteoporosis

Fosamax: Is Long Term Use of Bone Strengthening Drug Linked to Fractures?

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